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Calcium
May Prevent Travelers' Diarrhea
By Darin Ingels, ND
Healthnotes Newswire
(November 6, 2003)People suffering from infectious diarrhea (Travelers'
diarrhea) may get relief by consuming high-calcium milk products, according
to a new study in Gastroenterology (2003;125:46976).
Travelers' diarrhea
affects two of three tourists visiting Asia, Africa, and South America.
However, it is also common in Western societies as the result of food
or water contamination (food poisoning). Diarrhea is the worlds
second leading cause of death after heart disease. Young children, elderly
adults, and people with immune-suppressive diseases may be at higher risk.
The most common cause of travelers' diarrhea is a bacterium called E.
coli. While the symptoms are often self-limiting and resolve in a few
days, they can cause great discomfort. Treatment is usually supportive,
focused on making sure that fluid and electrolyte intake is maintained.
This is the first human study to suggest calcium has a protective effect
against E. coli.
In the new study,
32 healthy men between the ages of 20 and 55 years were intentionally
infected with a live but weakened form of E. coli. They were then randomly
assigned to consume approximately 3 cups of regular milk and 1 cup of
a milk-based custard per day (providing a total of 1,100 mg of calcium
per day) or the same amounts of low-calcium milk products (providing 60
mg of calcium per day) for three weeks. Bowel symptoms and fecal output
were measured initially and at the conclusion of the study. All participants
maintained a regular diet but excluded other dairy products and high-calcium
foods.
All participants developed
diarrhea shortly after being infected with E. coli. The men drinking the
regular milk had complete resolution of symptoms after the second day
of treatment, while the men drinking the low-calcium milk continued to
have diarrhea. The results of this study show that calcium in milk accelerates
recovery from infectious diarrhea.
Although this is the
first study in humans, preliminary animal research also showed that calcium
was effective in preventing infectious diarrhea. One animal study found
that oral calcium phosphate helped prevent E. coli infection, while another
study showed calcium protects against Salmonella infection. More human
research is necessary to determine if calcium might be effective against
other organisms that cause diarrhea.
Although it has not
been determined whether calcium from other food sources or from supplements
would provide the same benefit, individuals with milk allergy or lactose
intolerance might consider alternative sources of calcium. Foods high
in calcium include calcium-fortified soy products; nuts; green, leafy
vegetables (kale, collard greens, mustard greens); and seaweed.
Darin Ingels, ND,
MT (ASCP), received his bachelors degree from Purdue University
and his Doctorate of Naturopathic Medicine from Bastyr University in Kenmore,
WA. Dr. Ingels is the author of The Natural Pharmacist: Lowering Cholesterol
(Prima, 1999) and Natural Treatments for High Cholesterol (Prima, 2000).
He currently is in private practice at New England Family Health Associates
located in Southport, CT, where he specializes in environmental medicine
and allergies. Dr. Ingels is a regular contributor to Healthnotes and
Healthnotes Newswire.
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